Schedule

Sarah Kimmins, PhD - Université de Montréal

Germline epigenetic programming, reprogramming escape, mechanisms of inheritance, and experimental models for causality

Multigenerational cohorts, environmentally associated epigenetic variation, reproductive and developmental outcomes

Roundtable topics- Molecular Mechanisms of Epigenetic Inheritance- Genomics and Long-Read Sequencing Technologies- Epidemiology, Study Design, and Causal Inference- Evolutionary and Ecological Implications- Clinical and Public Health Translation Each table may identify- Unresolved questions- Experimental or analytical barriers

Exposure models, developmental epigenetic programming, sperm biology, comparative genomics, transposable elements, and emerging technologies

Moderator and Chair: Janice Bailey, PhD Panelists- Katharina Main, MD, PhD- Jorma Toppari, MD, PhD- Noora Kotaja, PhD- Kristian Almstrup, PhD- Jacquetta Trasler, MD, PhD- Gail Cornwall, PhD- Guillaume Bourque, PhD- Elin Grundberg, PhD- Eric Miska, PhD Discussion focus- Standards of evidence for epigenetic inheritance- Mechanisms with the strongest experimental support- Translation from experimental models to human populations- Long-read sequencing opportunities, limitations, and validation needs- Shared experiments, cohorts, technologies, and five-year priorities

Janice Bailey, PhD

End of the pre-meeting symposium on Epigenetic Inheritance

Beginning of the main CEEHRC meeting