
2026 CLS MX Data Collection School | 13th Edition
This hybrid MX school is a focused training program in Macromolecular Crystallography (MX) hosted by the Canadian Light Source (CLS) and the Canadian Macromolecular Crystallography Facility (CMCF). It is designed to guide participants through the full experimental pipeline, from sample preparation and data collection at a synchrotron beamline to data processing, with close support from experienced mentors.
Over three weeks (May 19-June 5), the hybrid format combines online lectures with in‑person, hands‑on beamtime to make the complex material more approachable in manageable segments. Participants will gain both conceptual understanding and practical skills in synchrotron‑based MX that are directly applicable to their own research projects.

How to Attend
Remote lectures will be delivered online, with times and meeting links provided to registered participants. On-site, hands-on data collection sessions will be held for a limited number of participants. The online portion is free, but a registration fee applies to the hands-on tutorials at the beamline. A maximum of 32 participants will be accepted for the in-person portion, so apply early to reserve your spot.
Program structure
1. Part I - Virtual Theory Lectures (for all participants)
The program opens with online lectures from May 19-22, with no lectures on May 21 for the CLS User Meeting. These sessions introduce participants to CLS and CMCF, as well as the core concepts and tools for the rest of the course. The goal is to provide a strong foundation so attendees can make the most of the hands-on components later. The lectures will cover:
CMCF Beamline Orientation for Remote Access
Introduction to X-ray Crystallography
Sample Preparation for Synchrotron MX
Data Collection Strategies
Principles of MX Data Processing
Participants are encouraged to engage with the CLS community by attending and presenting a poster virtually at the CLS User Meeting on May 21. This is an opportunity to showcase their work.
2. Part II - In-Person Hands‑on Data Collection Week at CLS (limited cohort)
From June 1-5, a limited group of participants will travel to CLS for an intensive, hands-on data-collection week. Each participant will be assigned beamtime on a CMCF beamline and will:
Operate the beamline under supervision
Collect diffraction data using either their own samples or standard crystals
Work through the data collection strategy with guidance from mentors
Because beamtime is limited, the in-person component is restricted to at most 32 participants on a first-come first-serve basis. The registration fee of $350 includes boxed lunches Monday to Thursday, breakfast Tuesday to Friday, and dinner on Thursday. Participants are expected to arrange their own travel and accommodation. Suggestions are provided in the Accommodation section of this site. Participants may also apply for travel support through the CLS Student Travel Program or the Larry Calvert Travel Award.
Participants are encouraged to bring their own samples for data collection at CMCF, making the experience directly relevant to their research questions. An optional informal lunch-and-learn session may be offered during the on-site week, providing opportunities for flash talks, discussion, and networking among participants and instructors.
Key details (TL;DR)
Dates (overall): May 19 - June 5
Format: Hybrid (online + in‑person at CLS)
Part I - Online Lectures (for all):
May 19-22
May 21 - CLS Annual User Meeting - Participants encouraged to present a virtual poster
Content: Orientation to CLS and CMCF, Introduction to Crystallography, Data Collection Strategies and Data Processing Theory
Part II - Hands‑on Data Collection at CLS (Max 32 Participants):
June 1-5
$350 Registration Fee, on‑site event at CLS
Content: Beamline operation and diffraction data collection on own or standard samples
Optional informal lunch‑and‑learn for flash talks and networking
Own samples strongly encouraged for data collection
Flash Talks (Optional)
Participants may show interest in presenting a Flash Talk at one of our on-site Lunch-and-Learn sessions, June 2-5, between 12 - 1 PM CST. Some points to keep in mind when preparing for your Flash Talk:
keep your talk between 5-15 minutes long,
Feel free to use slides or other visuals - you can share your screen during your Flash Talk,
If you are not comfortable sharing your unpublished or proprietary research, you can talk generally about a research area that interests you.
Linux Cheat Sheet
Download a PDF of these starter terminal commands here.
Location
Hybrid event:
Canadian Light Source - CMCF
44 Innovation Boulevard
Saskatoon, SK
Canada, S7N 2V3
Dates
Registration period:
February 13, 2026 - 9:00 AM CST - May 1, 2026 - 9:00 AM CDT
Contact us
If you have any questions, please contact michel.fodje@lightsource.ca
