EUDI 19 OCTOBRE 2023/ THURSDAY, OCTOBER 19^th, 2023

13:00 - Accueil des participants / Welcome of Participants

13:30 - 14:00 Mot de bienvenue/Welcome Address:
Michel Bouvier, PDG/CEO, IRIC - Université de Montréal
Daniel Jutras, Recteur/Rector, Université de Montréal
Ekat Kritikou, Vice-Dean, Research and Development at Faculty of medicine/ Vice-doyenne à la recherche et au développement. Faculté de médecine Université de Montréal
Marc Therrien, Chercheur principal (ancien Directeur scientifique) / Principal Investigator (previous Scientific Director), IRIC - Université de Montréal
Philippe Roux, Directeur scientifique/ Scientific Director, IRIC - Université de Montréal

Session I: Biologie cellulaire et métabolisme / Cell Biology and Metabolism
Modérateur/Moderator: Sébastien Carréno

14:00- 14:30 Insights Into the Subcellular Travels of Cellular RNAs and RNA Binding Proteins
Éric Lécuyer - IRCM, Montreal, QC, Canada

14:30 - 15:00 Metabolic determinants of advanced breast cancers
Julie St-Pierre - University of Ottawa, Ottawa, ON, Canada

15:00 - 15:15 1^e présentation courte| 1^st short presentation | Reda M. Zellag | IRIC | Microtubule force generators govern spindle orientation along two distinct axes in mitotic C. elegans germ cells.

15:15 - 15:45 Pause-Café | Coffee Break

15:45 - 16:15 Maintaining mitotic fidelity in complex in vivo environments
Abigail Gerhold - McGill University, Montreal, QC, Canada

16:15 - 16:45 Engineered Allelic Series: Unraveling the Complexity of Protein Function
Stéphane Pelletier - Indiana University, Indianapolis, IN, USA

16:45 - 17:15 2^e présentation courte | 2^nd short presentation | Lara Elis Alberici Delsin

17:15 - 17:30 3^e présentation courte| 3^rd short presentation | Sarah Denford

17:30 - 21:00 Cocktail dînatoire spécial 20^e anniversaire/Special 20^th Anniversary Cocktail Dinner

VENDREDI 20 OCTOBRE 2023/ FRIDAY OCTOBER 20^th, 2023

08:00 - Accueil des participants / Welcome of Participants

Session II: Signalisation cellulaire/ Cell Signaling
Modérateur/Moderator: Sylvain Meloche (TBC)

8:30 - 9:00 Promoting tissue regeneration through control of Wnt-beta-catenin signalling
Stéphane Angers - University of Toronto, Toronto, ON, Canada

9:00 - 9:30 Unravelling the molecular mechanisms controlling breast cancer metastasis: Exploring dormancy
Jean-François Côté - IRCM, Montreal, QC, Canada

9:30 - 10:00 Exploring the specificity in proximal proteome recruitment associated with kinase fusions
Anne-Claude Gingras - Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada

10:00 - 10:15 4^e présentation courte | 4^th short presentation | Mathieu Tremblay | IRIC | Preclinical Efficacy of Trametinib in Combination with Chemotherapy in T-cell Acute Lymphoblastic Leukemia

10:15 - 10:45 Pause-Café | Coffee Break + Expo. commanditaires| Sponsors Expo.

10:45 - 11:15 Structural principles of eukaryotic signaling
Frank Sicheri - Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada

11:15 - 11:45 Signaling from the nuclear envelope- fertility, chromatin and mechanotransduction
Helen McNeill - Washington University in St. Louis, St. Louis, MO, USA

11:45 - 12:15 Control of IL-23-dependent inflammation by a new class of cyclophilin A ligands
Stefano Marullo - Institut Cochin, Paris, France

12:15 - 13:30 Dîner | Lunch + Atelier carrière | Career Workshop

12:30 - 13:20 ATELIER CARRIÈRE: l’IRIC et la diversité des carrières scientifiques| CAREER WORKSHOP: IRIC and the Diversity of Scientific Careers
Animé par/ Led by: Julie Mantovani
Myreille Larouche, Agente de communications/ Communications Officer, IRIC
Simon Mathien, Responsable de la plateforme de criblage à haut-débit /Manager of the High-Throughput Screening Core Facility, IRIC
Neethi Nandagopal, Development Scientist (Immunology) CellCarta
Josette-Renée Landry, PDG/ President and CEO Génome Québec (TBC)

Session III: Immunité et cancer/ Immunity and Cancer
Modératrice/ Moderator: Trang Hoang

13:30 - 14:00 Pro-survival factor BCL-XL as a therapeutic vulnerability of infant acute megakaryoblastic leukemia
Sonia Cellot - CHU Ste-Justine, Montreal, QC, Canada

14:00 - 14:30 Phagosome proteomics: from 2D gels to ultra-sensitive mass spectrometry
Matthias Trost - Newcastle University, Newcastle, UK

14:30 - 15:00 Deciphering B (and T) cell responses to ovarian cancer
Céline Laumont - BC Cancer - Victoria, Victoria, BC, Canada

15:00 - 15:15 5^e présentation courte | 5^th short presentation | Laurence Côté

15:15 - 15:45 Pause-Café | Coffee Break + Expo. commanditaires| Sponsors Expo.

Session IV: Stabilité du génome/ Genome Stability
Modérateur/Moderator: Marc Therrien

15:45 - 16:15 Human diversity in the context of genomics, transcriptomic and proteomics
Unnur Þorsteinsdóttir - University of Iceland, Reykjavík, Iceland

16:15 - 16:45 Charting genome maintenance pathways
Daniel Durocher - Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada

16:45 - 17:15 Hanging by a thread : regulation of single-stranded DNA generation during replicative stress
Hugo Wurtele - Université de Montréal, Montreal, QC, Canada

17:15 - Mot de clôture par/ Closing remarks by Vincent Archambault, Chercheur principal/ Principal Investigator, IRIC - Université de Montréal