Research in the Nemerow lab is focused on gaining better understanding of adenovirus interactions with host cells. We investigate basic mechanisms involved in virus attachment, internalization and nuclear localization. A major focus of these studies is the signalling events initiated by cell integrins that promote adenovirus endocytosis

Scopus Author ID: 7006062087

Carmen San Martin is interested in the structural and physical principles that govern assembly and stabilisation of complex viruses. As a model system she uses adenovirus, a challenging specimen of interest both in basic virology and in nanobiomedicine. Her group approaches the problem from an interdisciplinary point of view, combining biophysics, computational, structural and molecular biology techniques. Accurate knowledge of adenovirus structure and biology is fundamental to both the discovery of anti-adenovirus drugs and the design of new, efficient adenoviral therapeutic tools.

Scopus Author ID: 57219832626

Andre Lieber is working on basic and translational aspects of adenoviruses. He was involved in the discovery of two of the known three receptors that are commonly used by human adenoviruses and demonstrated that intravenously injected adenovirus vectors trigger critical innate toxicity. His lab was the first to show that adenoviruses interact with blood coagulation factors and that this influences in vivo tropism and they also made contributions to a better understanding of how adenoviruses spread in epithelial tissues. He is also a scientific co-founder of a start-up company aiming to support the clinical translation of the in vivo hematopoietic stem cells gene therapy approach.

Scopus Author ID: 7005749586