8:45-9:00 Fayeza Ahmad Clinical or Population Health De-Frailing Cardiac Inpatients with a Multicomponent Intervention in the TARGET-EFT Randomized Clinical Trial 9:00-9:15 Kevin Comeau Basic Science Memory Gamma Delta T Cells Play a Role in Hypertension 9:15-9:30 Khalil Anchouche Clinical or Population Health Long-term effects of Lipoprotein(a) on Aortic Valve Calcium incidence and progression in the Multi-Ethnic Study of Atherosclerosis 9:30-9:45 Francisco Rios Basic Science Spike protein 1 of SARS-CoV-2 increases endothelial cell dysfunction via Interferon activation pathways 9:45-10:00 Hristo Valtchanov Basic Science In-Silico Assessment of the Affect of Hemolysis on Thrombosis in Ventricular Assist Devices 10:00-10:15 Zahra Sohani Clinical or Population Health Sex differences in the effectiveness of angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and sacubitril-valsartan in heart failure

10:30-10:45 Brandon Shokoples Basic Science P2RX7 antagonism blunts angiotensin II-induced hypertension, vascular injury and CD8+ T cell activation without the cardiac dysfunction induced by P2rx7 knockout 10:45-11:00 Leila Haririsanati Clinical or Population Health Accuracy of Native Myocardial T1 and T2 mapping for Quantifying Ischemic Myocardial Injury 11:00-11:15 Ida Derish Basic Science Interpatient Differences in Induced Pluripotent Stem Cell-Derived Cardiomyocytes After Hypoxia 11:15-11:30 Justin Miron Clinical or Population Health Effect of serum lipoprotein(a) levels on the progression to atherosclerotic cardiovascular disease in carriers of familial hypercholesterolemia variants 11:30-11:45 Shiwon Choi Basic Science Docetaxel is an anti-dyslipidemic and anti-atherogenic drug candidate 11:45-12:00 Mohammad Sazzad Hasan Clinical or Population Health Flexible Modeling of the Association Between Cumulative Exposure to Low-Dose Ionizing Radiation from Cardiac Procedures and Risk of Hematopoietic Cancer in Children with Congenital Heart Disease

2020 Lucian Award Recipient Dr. David A. Kass, M.D. Dr. Kass received the 2020 Lucian Award for his work on several new methods to treat heart failure with reduced ejection fraction. These studies include a form of nitric oxide called nitroxyl, an inhibitor of phosphodiesterase types 1 and 9, mutant forms of a protein involved in proteostasis called Chip and using a novel pacemaker strategy termed pacemaker-induced transient asynchrony. He pioneered research into the function of Protein Kinase G in heart muscle and how its activation can benefit heart disease. This has resulted in new discoveries with applications to heart failure, obesity, muscular dystrophy, cardiac hypertrophy and fibrosis and immune approaches to cancer therapy.

1:00: Rosie Fountotos Multicomponent Geriatric Intervention for Frail Hospitalized Older Adults with Cardiovascular Disease: The TARGET-EFT Randomized Clinical Trial 1:10: Johnathan (Yoni) Grossman Pulmonary valve replacement in Tetralogy of Fallot: Risk of redo and comparison to the Ross procedure in a pan-Canadian study 1:20: Justine Desrochers Risk Factors Modify the Strength of a Coronary Artery Disease Genetic Risk Score 1:30: Anouar Hafiane Apolipoprotein A-I carboxy-terminal domain residues 187-243 are required for adiponectin-induced cholesterol efflux 1:40: Amanda Guerin Genetic Testing for Familial Hypercholesterolemia in the Province of Québec: Update on a Retrospective Cohort Study 1:50: Kate Lindsay Sex and body composition differentially impact the myocardial oxygenation response to breathing maneuvers