06:30 - 07:30 EDT
Roddick Gates
Morning Hike/Run – Mount Royal
(meet at Roddick gates, McGill University)
Preliminary Program
* All times are based on Canada/Eastern EST.
06:30
Canada/Eastern
08:30
Canada/Eastern
09:00
Canada/Eastern
10:00
Canada/Eastern
10:00 - 11:15 EDT
Jeanne Timmins Amphitheatre, The Neuro
Session 1: Normal Development & Aging
· Specification & circuit assembly: lineage → projection logic; wiring rules that scale from development into adulthood · Sleep, arousal & state transitions: REM/NREM control, arousal and attention, spatiotemporal scales of basal-forebrain dynamics · ACh-NE-DA-5HT crosstalk: combinatorial receptor logic; network-level models predicting behavior and age-related compensation · Panel (15): From developmental rules to resilient aging
11:30
Canada/Eastern
11:30 - 12:45 EDT
Jeanne Timmins Amphitheatre, The Neuro
Session 2: Neuropsychiatric Syndromes & Risk
· Attention disorders & executive dysfunction: cholinergic signatures and target engagement · Schizophrenia & depression: receptor/subcircuit hypotheses and state-coupling deficits · Substance use disorders (SUD): habituation, salience, and ACh interaction with DA/NE systems · Panel (15): Who to treat, when, and why (vulnerability → intervention windows)
14:15
Canada/Eastern
14:15 - 15:30 EDT
Jeanne Timmins Amphitheatre, The Neuro
Session 3: Degeneration Mechanisms
· Tau/α-syn interfaces with cholinergic dysfunction (cellular & circuit) · Neuroinflammation & immune-cholinergic crosstalk · Vascular/metabolic contributors to cholinergic vulnerability · Panel (15): From mechanism to target
