Keynote Lecture 2 Marco Prado (Western University) “Dysregulation of chaperones in neurodegenerative diseases” Invited Speakers Joel Watts (University of Toronto) “α-Synuclein strains as drivers of disease heterogeneity” Mahmoud Pouladi (University of British Columbia) “Hunting partners: discovering novel HTT protein interactions using HD pluripotent stem cells” Gary Armstrong (McGill University) “Zebrafish ALS models of TDP-43 and FUS” Maria Vera Ugalde (McGill University) “Imaging single mRNAs uncovers neuronal mechanisms to sustain protein homeostasis” Selected short talks from abstracts Patrick Lajoie (Western University) “pH-dependent modulation of polyQ aggregation and toxicity in a yeast model of aging” Heather Durham (McGill University) “Challenges of inducing the heat shock response to treat ALS”