Workshops - First set
Location: VND 1831 and VND 1853
Demystifying bioinformatics: introduction to RNA-seq analysis in R- Félix Distéfano-Gagné (30 min)
Start with Group A VND 1831
This workshop aims to demystify bioinformatic analysis. Students will first be briefly familiarized with the different steps downstream of RNA-sequencing. Then, through a guided example, students will perform a basic differential expression analysis using their own computer. Overall, this will provide students with the tools necessary to conduct and analyze their own RNA-seq experiments.
(suggested background reading) Love et al, Genome Biol, 2014 (doi: 10.1186/s13059-014-0550-8) [method used for differential expression analysis]. Machado Xavier et al, bioRxiv, 2022 (doi: 10.1101/2022.08.04.502805) [preprint, source of provided datasets]
Demystifying genome editing - Jacques P Tremblay (30 min)
Start with Group B VND 1853
The workshop will present the CRISPR/Cas9 technology and the Prime editing technology derived from the CRISPR/Cas9. The Prime editing technology permits to replace any targeted nucleotide by the desired nucleotide. This technology may permit to correct point mutation responsible for thousands of hereditary diseases.