June 29 to July 4, 2025

2025 15th Tooth Morphogenesis & Differentiation Conference (Corfu, Greece)


The present conference on Tooth Morphogenesis and Differentiation has been a European intellectual institution starting in 1978 and continuing with 14 individual meetings until its present incarnation in 2025. TMD focuses on a broad range of topics centering on tooth morphogenesis and differentiation. Over the years, the meeting has come to include a broad range of topics mostly centering around craniofacial development and evolution. From a disease perspective, this conference also has become a forum for a plethora of craniofacial birth defects, offering novel insights toward deciphering mechanisms and finding therapeutic avenues.

Official announcement of the event

We are pleased to announce that the 2025 15th Tooth Morphogenesis & Differentiation Conference will be held in Corfu, Greece, from Sunday, June 29 to Friday, July 4, 2025!

Enter these dates in your agenda and keep an eye on our website for all the details.

The deadline for the registration and submission deadline is July 1st, 2025.

We look forward to seeing you there!

Petros Papagerakis, Université Laval, Québec, Canada (Organizer)
Tom Diekwisch, University of Rochester, Rochester, USA (Co-Organizer)

This conference offers 35 training credits.

Official announcement of the event

Chair: Petros Papagerakis

CoChair: Thomas Diekwisch

Accommodation : https://corfuholidaypalace.gr/en/

Awards

• Young investigator awards for students and Post-Docs

• Diversity travel awards for students and Post-Docs

Objectives of the Conference

To address critical unresolved issues in the field of tooth development research such as

o (1) in-depth understanding of the mechanisms involved in tooth formation and replacement through evolution and comparative anthropology and zoology

o (2) elucidating the complex mechanisms that contribute to tooth morphogenesis and patterning

o (3) research on the contribution of dental stem cells toward tooth initiation, development, and repair along species boundaries and through aging

o (4) discussions about the pathogenesis of dental pathologies and underlying physiological, genetic, and environmental factors within the context of the whole organism, and how studies of tooth formation and its structural and mechanical properties can inform new biomimetic materials and new bioinspired strategies for tissue repair and regeneration.

o (5) training of early investigators by exposure to career development and novel techniques.

Objectives of the Conference

Keynote and Invited Speakers

  • Agnes Block-Zupan

    Agnes Block-Zupan

    Strasbourg, France

    Birth defects and next generation sequencing. Agnes Bloch takes a fresh look at Wittkop’s classic classification of enamel defects using recent molecular tools. This new strategy uncovered more than 30% novel phenotypes, most prominently MMP20 and Fam83H. This revised knowledge will greatly affect patient care.

  • Kristin Bruk Artinger

    Kristin Bruk Artinger

    Minneapolis, USA

    Polycomb proteins are major determinant of neural crest in zebrafish and humans. This presentation will discuss how epigenetic factors contribute to development and differentiation.

  • Axel Visel

    Axel Visel

    Berkley, USA

    Dr. Visel developed and applied novel computational and experimental sequence-based methods for elucidating the gene regulatory landscape of vertebrate genomes, which led to the discovery of thousands of genetic switches implicated in developmental and disease processes in the human genome. This work has led to an understanding of the fine tuning of craniofacial morphology by distant-acting developmental enhancers.

  • Katsu Takahashi

    Katsu Takahashi

    Kyoto, Japan

    Targeting USAG-1 shows promise for treating missing congenital tooth. Anti-USAG-1 neutralizing antibodies have been developed and will progress towards clinical trials, which may regenerate missing congenital teeth in conditions, such as hypodontia and oligodontia. The protocol framework for a phase 1 study has been finalized, and preparation for future studies is underway. A summary of the early findings will be presented.

  • Luiz Eduardo Bertassoni

    Luiz Eduardo Bertassoni

    Portland, USA

    Dr. Bertassoni's research studies the use micro-scale technologies and bioprinting for tissue engineering; nanoscale structural and mechanical properties of mineralized tissues; and different aspects of the emerging field of ‘organs-on-a-chip’.

  • Rena N. D’Souza

    Rena N. D’Souza

    USA

    Dr. Rena D’Souza recently retired as the ninth Director of the National Institute of Dental and Craniofacial Research, National Institutes of Health. She was deeply committed to the organization’s mission which is to advance fundamental knowledge about dental, oral, and craniofacial health and disease and translate these findings into prevention, early detection, and treatment strategies that improve overall health for all individuals and communities across the lifespan. As a clinician- scientist, D’Souza has been strongly committed to education, discovery and mentoring throughout her academic career, mostly in the field of dental genetics.

  • Jim Simmer

    Jim Simmer

    Michigan, USA

    Professor Simmer is an active Emeritus Professor at the University of Michigan School of Dentistry. Most recently Dr. Simmer has been analyzing genetic data to build comprehensive models to explain how the genes associated with inherited enamel malformations normally function to extend enamel mineral ribbons during the secretory stage and harden enamel during maturation.

  • Ophir Klein

    Ophir Klein

    An important underpinning of regenerative medicine is to understand the mechanisms by which mammals naturally use stem cells to heal tissues. I will discuss work on renewal and plasticity in the oral mucosa and dentition, and I will share thoughts about the potential therapeutic implications of progress in developmental and stem cell biology.

  • John Bartlett

    John Bartlett

    Dr. Bartlett has focused his research on understanding the proteinases involved in dental enamel development and he has also studied the molecular mechanisms that cause dental fluorosis. He and his collaborators discovered matrix metalloproteinase-20 (MMP20, Enamelysin) and kallikrein-related peptidase-4 (KLK4). Recently they demonstrated that A Disintegrin And Metalloproteinase Domain-10 (ADAM10) secreted by ameloblasts is essential for proper enamel formation, which will be the subject of Dr. Bartlett’s presentation.

  • Faleh Tamimi

    Faleh Tamimi

    Prof. Faleh Tamimi is currently serving as Research Coordinator of the College of Dental Medicine. Prof Tamimi holds a PhD degree in Biomaterials and specialty degrees in Geriatric dentistry and implant prosthodontics. His multidisciplinary and translational research covers various areas including the fields of biomaterials, mineralized tissues, tissue regeneration, inflammation, and chronobiology.

Location

Corfu Holiday Palace

2 Nafsikas Kerkira Grèce, 491 00

Registration period

September 18, 2024 - 12:00 AM until July 1, 2025 - 11:59 PM

Submission period

September 18, 2024 - 12:00 AM until July 1, 2025 - 11:59 PM

Contact us

If you have any questions, please contact tmd2025@fmd.ulaval.ca .

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