12:30 Arrival and registration 13:30 Trainee Research showcase (10 min talk + 5 min questions) of graduate and postdoctoral students) Chair: Susan George Opening 1- Sungsoo Yoo: New detergent conditions for studying prototypical Class A receptor interactions with ß-arrestin1 in cryo-EM 2-Louis-Philippe Picard: Determining Factors in G protein selectivity and efficacy for the Adenosine A2a receptor 3-Madeline Power: Exploring the molecular promiscuity of L-Phenylalanine (Phe) activation of G protein-coupled receptors 4-Jordan Mattheisen: Enhancing GPCR drug fragment affinity in live cells using genetic code expansion and bioorthogonal covalent tethering 5- Natalie Hewitt Valentin: Non-catalytic functions of the catalytic glutamine in G proteins 6- Khaled S. Abd-Elrahman: Activation of M1 Acetylcholine receptors improves cognitive deficits and hallmarks of Alzheimer’s disease in APPswe/PSEN1ΔE9 mice 7- Supriya A. Gaitonde: Towards elucidating the polypharmacological fingerprint of antipsychotic drugs 8- Henry A. Dunn: Endogenous trans-synaptic allosteric modulators of group III mGluRs in neuropsychiatric disease 9- Kyla Bourque: A tale of three cell types: moving beyond HEK 293 cells towards primary and iPSC-derived cardiomyocytes to understand disease-relevant signalling 15:45 Coffee Break 16:15 Welcoming Remarks (Martin Beaulieu) Dedication to Marc Caron's memory. (Michel Bouvier) 16:30 KEYNOTE SPEAKER, MARC CARON CONFERENCE Chair: Martin Beaulieu Stephen Ferguson, University of Ottawa, Canada Regulation of Metabotropic Glutamate Receptor Signaling: Role in Huntington’s and Alzheimer's Diseases 17:30 Welcome reception and Poster Session I (odd numbered posters) (odd number posters should be put on before the session begins and taken down before lunch on May 13.) 19:30 Dinner