Rising Star in Bio-Imaging in Quebec lecture
By presenting the annual Rising Star in Bio-Imaging in Quebec Award, QBIN highlights the work of an emerging researcher in the field of bio-imaging.
Dr. Matthieu Pelletier-Galarneau, Montreal Heart Institute
Please note this lecture will be held in French
Imagerie moléculaire des maladies cardiovasculaires par tomographie par émission de positrons
L'imagerie moléculaire cardiovasculaire, grâce surtout à la tomographie par émission de positrons, a connu un essor incroyable au cours des deux dernières décennies avec l'émergence de nombreuses nouvelles applications cliniques. Durant cette présentation, qui se veut accessible à tous les membres du RBIQ, je discuterai des deux principaux axes de développement qui ont permis l'expansion des indications cardiovasculaires de l'imagerie moléculaire, soit la quantification de la perfusion myocardique et l'imagerie des infections et inflammations cardiovasculaires. J'en profiterai pour souligner quelques-unes de nos contributions et exposer l'étendue des possibilités de l'imagerie moléculaire cardiovasculaire en recherche par un survol de différents projets en cours dans notre laboratoire.
Matthieu Pelletier-Galarneau
Dr. Pelletier-Galarneau is a nuclear medicine physician and Head of Nuclear Medicine at the Montreal Heart Institute and a FRQS clinician-scientist, in addition to being a clinical associate professor at the Faculty of Medicine of the Université de Montréal in the Department of Radiology, Radiation Oncology and Nuclear Medicine.
He has a strong background in cardiovascular imaging and extensive experience in advanced clinical and basic research.
After completing a bachelor's degree in physics-mathematics, he enrolled in the MD-MSc program at Université de Montréal. Then, after a subspecialization in clinical and preclinical PET/MR imaging at Harvard University, he returned to nuclear medicine at the Heart Institute.
His research, both clinical and basic, focuses on cardiovascular applications of molecular imaging.
William Feindel Lecture
The William Feindel Lecture honours a scientist who has made significant contributions to the field of imaging.
Dr. Sandra Black, University of Toronto
Intersection of misfolded proteins and vasculopathies - what, why and where in aging and dementia
In her talk, Dr. Black will cover the following learning objectives:
1) Illustrate that comorbid neurodegenerative pathologies and vascular disease are often the rule not the exception in the common dementias.
2) Review the subtypes of MRI-visible macro and microvascular disease and the culprit misfolded proteins that have been characterized by post-mortem, by CSF and PET, and recently as a game changer-- in plasma
3) Highlight how rapid advances in multiple-modality imaging both PET and MRI, enhanced by Machine Learning methods, further informed by genetics, cerebrospinal fluid and recently plasma biomarkers are opening the door to Precision Diagnosis and Medicine for Alzheimer’s and other dementias
4) Overview the parallel rapid development of potential Disease Modifying Therapies, which promise a new era of secondary prevention and mitigation, while also noting the key role of treatment advances for vascular health and emphasizing the key role of lifestyle choices.
Sandra Black
Sandra E Black, O.C., O.Ont., Hon.DSc., MD, FRCP(C), FRSC, FANA, FAHA, FAAN, Professor of Medicine (Neurology Division) at Sunnybrook HSC, U Toronto, is an internationally known cognitive and stroke neurologist, who has been actively engaged in > 70 pharmaceutical trials in the last 3 decades, including recent potential Disease Modifying Therapies. She has published >650 peer publications (+70 invited) (Google HI 132; 76,969 citations) in a research career bridging dementia and stroke, using standardized, quantitative neuroimaging, cognitive, functional and neuropsychiatric the measures, genetics, and neuropathology to study brain-behavior relationships across the common dementias, with a focus on inter- relationships of Small Vessel Disease and neurodegeneration (brainlab.ca). In the Research.com 2022 ranking of the top cite 1000 women scientists world-wide, she was ranked 8th in Canada and 298th in the world. Dr Black was inaugural Executive Director of the Toronto Dementia Research Alliance (2012-20), a collaboration of U of T’s university hospital memory programs, which assess >2000 new patients a year, potentially linkable with consent, to the Institute of Clinical Evaluative Sciences for Health Services research. (https://tdra.utoronto.ca). In 2020, she became Scientific Director of the Dr. Sandra Black Centre for Brain Resilience and Recovery, through a $10M anonymous lead gift. She has served on the Executive Committee for the Alzheimer’s Disease Neuroimaging Initiative (ADNI) since 2011. Recognitions include Fellowship, Royal Society of Canada, U of Toronto’s Faculty of Medicine Dean’s Lifetime Achievement Award, an Honorary Doctor of Science from Waterloo University, the Distinguished Achievement Award of AAN’s Society of Cognitive and Behavioral Neurology, University of British Columbia’s 2022 Margolese Brain Disorders prize, recognizing Canadians who have made outstanding contributions to amelioration and treatment of brain disorders, and the Bill Thies Distinguished Service Award from the Alzheimer Association International Congress (2022). She was appointed Member of the Order of Ontario (2011) and Officer of the Order of Canada (2015) for her contributions to Alzheimer’s disease, stroke and vascular dementia.
