Chair: Florian Groeber-Becker Ulrich Dirnagl , QUEST Center for Transforming Biomedical Research, Berlin Institute of Health, Berlin (Germany) - ZOOM; Julia Schüler , Therapeutic Area Lead Oncology at Charles River Discovery Research Services Germany GmbH, Freiburg (Germany); Marian Raschke , Bayer AG, Research & Development, Pharmaceuticals, Advanced Cellular Models, Berlin (Germany); Dilyana Filipova , Doctors Against Animal Experiments, Cologne (Germany)

Chair: Antje Appelt-Menzel / Winfried Neuhaus 10:00 - 10:30 Valentin Wegner "Organ-on-chip - emerging in vitro models in dissecting host-pathogen interaction", Institute of Biochemistry II, Center for Sepsis Control and Care, Research Group INSPIRE, Jena University Hospital, Jena (Germany) 10:30 - 10:45 Fulya Ersoy "Monitoring Neurosphere electrophysiological activity using a novel NeuroMPS with integrated microelectrodes", NMI Natural and Medical Sciences Institute, University of Tübingen, Tübingen (Germany), Selected talk #30 10:45 - 11:00 Jan Hansmann "Automation and Artificial Intelligence in the context of 3R", Fraunhofer ISC, Translational Centre Regenerative Therapies TLC-RT and University of Applied Sciences Würzburg-Schweinfurt, Würzburg (Germany), Selected talk #26 11:00 - 11:15 Alessia Moruzzi "SpheroFlow: a user-friendly Heart-on-Chip integrating hiPSC-derived cardiac 3D microtissues amenable for multi-parametric non-invasive monitoring", NMI Natural and Medical Sciences Institute, Reutlingen (Germany), Selected talk #66

Chair: Christian Lotz / Michael Oelgeschläger 11:30 - 12:00 Michael Oelgeschläger "Development and standardisation of (complex) in vitro test methods: challenges and concepts", German Federal Institute for Risk Assessment (BfR), Unit Strategies for Toxicological Assessments, Berlin (Germany); 12:00 - 12:30 Katharina Koch "In vitro tests to replace Developmental Neurotoxicity (DNT) studies", DNTOX GmbH and Leibniz Research Institute for Environmental Medicine, Düsseldorf (Germany) 12:30 - 12:45 Svenja Wingerter "Integration of biological membranes into Organ-on-Chip systems to model age-related macular degeneration", Department for Microphysiological Systems, Institute of Biomedical Engineering; Institute for Ophthalmic Research, Department for Ophthalmology, Eberhard Karls University Tübingen, Tübingen (Germany), Selected talk #72

Chair: Silke Riegger / Marco Metzger 13:45 - 14:15 Jennifer Rosowski "Charite 3R", Charité - Universitätsmedizin Berlin Campus Virchow-Klinikum, Berlin (Germany); 14:15 - 14:45 Rene Tolba "3R Competence Network NRW", RWTH Aachen University, Institute for Laboratory Animal Science & Experimental Surgery and Central Laboratory for Laboratory Animal Science, Aachen (Germany); 14:45 - 15:00 Florian Groeber-Becker "Würzburg Initiative 3R - WI3R", Fraunhofer ISC, Translational Centre Regenerative Therapies TLC-RT, Würzburg (Germany)

Prof. Florian Groeber-Becker ; Best talk and best poster prize (on-site voting by the auditorium until Friday lunch time) Travel awards (3x) Wrap-up and outlook